Post-translational modification by the small ubiquitin-like modifier, SUMO can modulate the activity of its conjugated proteins in a plethora of cellular contexts.The effect of SUMO conjugation of proteins during an immune response is poorly understood in Drosophila.We have previously identified that the transcription factor Jra, the Drosophila Jun
Honey bee colonies face significant threats from pathogens and pests, including chalkbrood disease caused by Ascosphaera apis and Varroa destructor mites.Traditional monitoring methods for these issues are often destructive, hindering continuous and detailed observations.This study introduces a novel, non-destructive monitoring technique using a mo
Despite the progress made to improve therapeutic FAN outcomes for acute myeloid leukemia (AML), many unmet clinical needs remain to be resolved.Unlike existing anti-AML strategies, here we developed a biomimetic nanocomposite to efficiently eliminate the leukemia cells in the bone marrow and prevent the homing of AML.To fulfill our design, the ultr
Risperidone is an atypical antipsychotic Shampoos that antagonizes 5HT2A and D2 receptors.Risperidone is used for many indications in children and adolescents.These indications include bipolar mania, schizophrenia, disruptive behaviour disorders, and aggression associated with autism spectrum disorder/mental retardation.Although it is usually well